We address fundamental questions in biology from a physicist’s perspective, combining theoretical and experimental approaches.
We investigate the role of stochasticity in genetic regulation and in the evolution of ecosystems, the effects of the evolutionary process on the features of living systems, and we develop new approaches both in synthetic biology and in the field of biomaterials.
Genetic circuits : regulation, fluctuations and engineering
- Global regulation of genetic expression in bacteria (H. Geiselmann)
- Circadian cycles in bacteria [Fr] (I. Mihalcescu)
- Non-genetic individuality in bacteria [Fr] (I. Mihalcescu)
- Gene regulation by the RpoS sigma factor of E. coli (S. Lacour)
- Regulation of curli production and biofilm formation (S. Lacour)
- Dynamics and design of RNA systems (A. Dawid)
Evolution
- Ecosystems and biodiversity [Fr] (B. Houchmandzadeh & M. Vallade)
Biotechnologies and biomaterials
- Structure and dynamics of biological polymers [Fr] (E. Geissler)
Experimental platform
- M2Bio (N. Scaramozzino & C. Pinel)