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PhD offer Connectomics Bone

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We are currently seeking a talented PhD candidate to better understand the role of complex cellular networks in mineralized tissues (bones & teeth). The analysis of complex networks is a fascinating field with incredibly varied applications : social networks interactions, logistic transport, telecom and computing infrastructures etc. It is also a cornerstone of neuroscience, where biologists seek to understand the relations between measured functions and the brain organization. At the most fundamental level, this implies understanding how the topology/connectivity of the neuron network determines higher scale functions and vice versa. Interestingly, few people know, that there are as many cells in the human skeleton as there are in the brain and that both have a similar dendritic phenotype, i.e. are highly interconnected as seen on the fluorescence microscopy image on the left showing interconnected cells surrounding a blood capillary in a human femur. It is therefore tempting to apply similar ideas developed in the general framework of complex networks analysis to bones.

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