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Accueil > Équipes > OPTique et IMAgeries > Instrumentation et Méthodes > Imaging systems

Minimally invasive optical resolution photoacoustic endoscopy

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The development of a minimally invasive photoacoustic microendoscope started a couple of years ago as part of the ERC Coherence project. The current prototype is limited to short and rigid multimode fibers, to avoid changes in the fiber configuration as required by the current calibration-based reconstruction approach. One main objective of the next few years will be to develop a calibration-free approach for imaging through multi-mode fiber. Achieving this objective would be a major breakthrough in the field of imaging through multi-mode fiber. We will also focus our efforts on developing a real-time imaging system, making use of DMD (Digital Micromirror Devices) to run the system at several tens of kHz, whereas the current prototype is still limited to in terms of imaging speeds.

Some envisioned approaches are detailed in the Wave manipulation section of the team’s project. While the objective of the Coherence project is to develop a photoacoustic endoscope, the approach is expected to work equivalently for fluorescence imaging. Our main goal is to build a minimally invasive prototype for hybrid photoacoustic/fluorescence microendoscopy, to be applied in particular to brain imaging of small animal in vivo, as detailed later in the section In vivo photoacoustic imaging.