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Impact of compressive stress on engineered cancerous tissues

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Cancer tumors in vivo are mechanically constrained by their environments, which can impact their growth and/or invasiveness. This project aims at studying how compressive stress regulate the growth and contractility of cancerous tissues. To this end, this project combines cutting edge technologies in microfabrication with tissue engineering. Microfabrication techniques allow for generating soft force microsensors between which 3D cancerous microtissues are engineered. This challenging internship will provide a highly interdisciplinary training, as the student will learn praised skills in different aspects of bioengineering, from materials science to fundamental biology and biophysics.