24 January 2022
Controlling ion channels activity using photoactivatable toxins
Photoactivatable toxins targeting ion channels, derived from animal venoms, have the potential to control the activity of excitable cells with high spatiotemporal precision. An international consortium including researchers from the LIPhy developed a new technology to cage these peptides, enabling precise spatiotemporal control of neuronal ion channels associated with excitability. This technology opens the gate for novel opportunities in translational research and light-guided therapeutic interventions.
