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Home > StagesPhysique du Vivant

StagesPhysique du Vivant

Articles with keyword "Physique du Vivant"

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Modelling the dynamics of a biological tissue in vivo

The mechanisms that cells employ to shape living organisms during embryogenesis remain elusive. Combining laser nanoablations and mechanical modelling we aim at a better understanding of the role (...)

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Multiscale analysis of the cellular networks in bone and dentin.

Morphometric studies of cell networks currently constitute an important challenge in bioimaging. The goal of this internship is to optimize the tools developed to analyze the cellular network on images compatible with a histological analysis routinely performed in laboratories dedicated to biological / biomedical analysis.

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Non contact measurement of mechanical properties of living tissues at microscale

In living organism, the exra-cellular matrix (ECM) has a significant role in questions such as cell adhesion, cell-to-cell communication and differentiation. Mechanical properties and mechanical (...)

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Optogenetic interrogation of cell-cell interaction

Mechanical signals, such as forces or stiffness, are crucial to many biological rocesses over a range of length scales. This project aims at studying how one cell’s contractility impact its (...)

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Optogenetic interrogation of engineered microtissues

Mechanical signals, such as forces or stiffness, are crucial to many biological processes over a range of length scales. This project aims at studying how these signals are spatially propagated (...)

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Remote control of a microswimmer through pressure waves

Microswimmers are a research subject extremely fruitful for a few years, both on the fundamental point of view (motility at small scale) and for more applicative purposes (e.g. targetted drug (...)

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Sensing intratissular mechanical pressure by measuring rotational diffusion

During morphogenesis, homeostasis or tumour development, mechanical cues are though to play an important role. However it is still almost impossible to measure, quantitatively, the mechanical pressure within a tissue.

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Synthetic biology of RNA

Our team develops a set of methods to engineer RNA systems with gene regulatory functions: “RNA switches”. On the one hand we develop numerical tools for designing RNA sequences using computer simulations of the dynamical folding of RNA, on the other hand we implement genetically the designed RNA switches and we test and characterize their gene regulatory function in vitro and in vivo in bacteria.

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