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StagesPhysique du Vivant

Articles with keyword "Physique du Vivant"

AFM characterization of gel particles - Application to living cells

This study is part of the ANR CellDance project which explores a new approach combining nanophotonics and microfluidics to measure the mechanical response of individual cells for diagnostic purposes. Indeed, the deformability of individual cells is an indicator of certain diseases such as malaria. In this master project, we propose a first study on the mechanical measurement of gel beads whose mechanical properties mimic those of red blood cells.

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Connectomic analysis of multiscale biological cellular networks

Morphometric studies of cell networks currently constitute an important challenge in bioimaging. The goal of this internship is to develop graph analysis including geometry and symmetry characteristics of the cellular network in bone.

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Molecular quantification of density and oligomerization

Counting and characterizing molecules in their biological environment is an important challenge for our fundamental understanding of life and for clinical prospects. In this internship, we will develop a technique called pbFFS for photobleaching Fluctuation Fluorescence Spectroscopy to quantify molecular oligomerization, clustering or aggregation, which mediate a myriad of biochemical processes.

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The Bacterial Nucleoid

The dynamics of the chromosomal DNA of bacteria is arguably simpler than that of eukaryotic cells. Indeed, it is not separated from the rest of the cytoplasm by the nuclear envelope, and its (...)

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