Laboratoire Interdisciplinaire de Physique

Blood is a complex fluid whose composition and physical characteristics tell us about a patient’s health. The rheology of blood can be modified by the phenomenon of aggregation of red blood cells (...)

Adherent cells can sense their physical environment (forces, rigidity, shape) and react to external mechanical stimuli. The translation of a mechanical signal into a biochemical cue (...)

Cancer is a leading cause of death worldwide. One of the cancer main features is the rapid proliferation of abnormal cells and their invasion into vital organs (metastasis). In order to invade other tissus, cancer cells migrate through the endothelium.

About 10 years ago a Nobel Prize was awarded to the invention of fluorescent proteins. Genetically encoded fluorescent molecules opened the route for a previously unimaginable amount of (...)

Understanding how adhesion sites sense varied external cues to modulate downstream signaling networks and cell–ECM force transmission is critical to elucidate the sensory mechanisms underlying invasion and tissue architecture.

Living cells come in a wealth of different shapes depending on their esurroundings. The organisation of their polymeric skeleton reflects this diversity. Using rheology approaches, we seek (...)

The goal of this project is to decipher the mechanical aspects of bacterial adhesion, in order to understand the relation between the mechanical environment of bacteria and their virulence. (...)

Microtubules are omnipresent tube-like polymeric structures in living cells. They serve as mechanical scaffold for cilia, flagella or axons and as intracelluar transport tracks. Throughout their (...)